Tend not to use tramadol hydrochloride tablets in clients getting MAOIs or within 14 times of halting such treatment.Recommend both equally patients and caregivers about the challenges of respiratory melancholy and sedation when tramadol hydrochloride extended-release tablets are used with benzodiazepines or other CNS depressants (including alcohol

• Stay away from using tramadol hydrochloride extended-release tablets in adolescents 12 to 18 decades of age who have other chance elements which will boost their sensitivity into the respiratory depressant effects of tramadol Except if the advantages outweigh the hazards.Reserve concomitant prescribing of such medications for use in individuals